8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Symphony
DepartsWed, Jul 1st 2026
ReturnsThu, Jul 9th 2026
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
The 180-passenger American Symphony introduces an updated modern interior design, integrating an elegant and refined aesthetic with our tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography acro… 
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 4th 2026
ReturnsSun, Jul 12th 2026
Nights8
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerica
DepartsWed, Jul 8th 2026
ReturnsThu, Jul 16th 2026
Nights8
Departing PortMemphis
Ports of CallMemphis, Mississippi River, Cleveland, Vicksburg, Natchez, St. Francisville, Cruising the River, Oak Alley, New Orleans
Launched in 2016, America is one of the finest Mississippi paddlewheelers ever built, introducing features never before seen on the Mississippi. America embodies a casual ambiance and relaxed atmosphere while providing panoramic views of the passing…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 11th 2026
ReturnsSun, Jul 19th 2026
Nights8
Departing PortSt Louis
Ports of CallSt Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 18th 2026
ReturnsSun, Jul 26th 2026
Nights8
Departing PortMinneapolis/St. Paul
Ports of CallMinneapolis/St. Paul, Mississippi River, La Crosse, Cruising the River, Dubuque, Davenport, Hannibal, St Louis (2 Days)
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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14 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Heritage
DepartsSat, Jul 25th 2026
ReturnsSat, Aug 8th 2026
Nights14
Departing PortPittsburgh
Ports of CallPittsburgh, Cruising the River, Marietta, Maysville, Cincinnati (2 Days), Louisville (2 Days), Henderson, Evansville, Paducah, Cruising the River, Cape Girardeau, St Louis (2 Days)
Built in 2015, American Heritage, formerly Queen of the Mississippi, will receive a total ship redesign in time for the 2022 cruise season.
From the staterooms and suites to the lounges and dining rooms, American Heritage will be completely remodeled wit…
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8 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Serenade
DepartsSat, Jul 25th 2026
ReturnsSun, Aug 2nd 2026
Nights8
Departing PortSt Louis
Ports of CallSt Louis, Mississippi River, Hannibal, Cruising the River, Muscatine, Dubuque, Winona, Red Wing, Minneapolis/St. Paul
Coming in 2023 – American SerenadeAmerican Cruise Lines is pleased to announce American Serenade, one of the newest ship in our revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Missis…
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
